Überlebensvorteil unter Regorafenib bestätigt

Erythema multiforme induced by regorafenib

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. © 2017 The Authors. Journal of General and Family Medicine published by John Wiley & Sons Australia, Ltd on behalf of Japan Primary Care Asso...

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Blutungen unter Antikoagulanzientherapie

Anticoagulation with vitamin K antagonists (VKAs) is effective in the prevention and treatment of thrombotic complications in many clinical conditions, including atrial fibrillation (that represents today the most frequent indication for anticoagulant treatment), venous thromboembolism, acute coronary syndromes and after invasive cardiac procedures. Bleeding is the most important complication o...

OpenID unter Sicherheitsgesichtspunkten

Der Authentifizierungsstandard OpenID ist im Web-2.0-Umfeld weit verbreitet. Ziel von OpenID ist es, dem Benutzer eine für alle OpenID unterstützenden Webseiten die gleiche Anmeldeprozedur zur Verfügung zu stellen, die zur Authentifizierung auf einen zentralen Dienst zugreift, so dass der Benutzer lediglich ein einziges Passwort verwalten muss. Dieser Beitrag beleuchtet den OpenID-Standard unte...

Single dose regorafenib-induced hypertensive crisis.

Gastrointestinal stromal tumors (GISTs) are uncommon tumors of the gastrointestinal (GI) tract. Regorafenib is a new multikinase inhibitor and is approved for the treatment of GISTs in patients who develop resistance to imatinib and sunitinib. The most common drug-related adverse events with regorafenib are hypertension, hand-foot skin reactions, and diarrhea. Grade IV hypertensive side effect ...